ChemInform Abstract: Practical and Efficient Chlorination of Deactivated Anilines and Anilides with NCS in 2-Propanol.
Abstract
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ChemInform Abstract
Deactivated anilines (I) and (III) and amides (V) are selectively monochlorinated with NCS in isopropanol. In situ generated isopropyl hypochlorite is suggested as chlorinating agent.