Preparative Organic Chemistry
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ChemInform Abstract: Synthesis and Pharmacology of New Dithiocarbamic Acid Esters Derived from Phenothiazine and Diphenylamine.
First published: 09 June 2010
Abstract
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ChemInform Abstract
Fourteen new esters such as (III) and (V) are synthesized and tested for antihistaminic and anticholinergic activities. The compounds show no significant anticholinergic activity. Esters (IIIc) and (Vc) exhibit moderate antihistaminic activity. In general, diphenylamines (V) are more active than phenothiazines (III).
