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ChemInform Abstract: Aminomethyl-2,6-difluorophenols as a Novel Class of Increased Lipophilicity GABAc Receptor Antagonists.
First published: 10 June 2010
Abstract
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ChemInform Abstract
Compound (I) is shown to act as a novel GABAc receptor antagonist with increased lipophilicity. The increased lipophilicity of this compound should facilitate crossing of the blood-brain barrier, which is essential for characterizing the role that GABAc receptors play in vivo and for drug development in general.
