ChemInform Abstract: Asymmetric Cyclization of meso-Diepoxides Using Chiral (Salen)Co(III)OAc Catalyst Forming Optically Active 1,4-Anhydropentitols and 2,5-Anhydrohexitols.
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
Asymmetric hydration of meso-diepoxides (I) and (III) in the presence of a chiral Co—salen complex proceeds with high enantioselectivity (>99% e.e.) to furnish 1,4-anhydropentitol (II) and 2,5-anhydrohexitol (IV), resp., in good yields. In the case of compound (III), the cyclization reaction is not totally regioselective and 1,5-anhydrohexitol (V) is obtained as side product.
