ChemInform Abstract: Double Annulation Route to Fused Bicyclic Compounds with Three Contiguous Quaternary Centers.
Abstract
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ChemInform Abstract
A stereoselective route towards bi- and tricyclic compounds featuring three new contiguous quaternary centers is discovered by reaction of a tethered bis(malononitrile) with alkynes. Two annulation modes are possible depending on the structure of the starting materials.