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ChemInform Abstract: Structure—Activity Investigations of Analogues of the C15—C26 Phorboxazoles Segment.
First published: 11 June 2010
Abstract
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ChemInform Abstract
Various substances, represented by the structure types (I)—(III), are prepared and tested for antifungal effects and cytotoxicity. The most potent agents are (I) and (II), although their activity is considerably lower compared to known macrolides such as epothilone A and B.
