ChemInform Abstract: A Convenient Synthesis of (Z)-3-(α-Cyano-α-alkoxycarbonylmethylene)-2-piperazinones and Their Derivatives.
Abstract
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ChemInform Abstract
Condensation of dialkyl (E)-2,3-dicyanobutenedioate (I) with diamines (II) and (IV) gives 2-piperazinone derivatives (III) and (V).