Volume 29, Issue 40
Natural Products
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ChemInform Abstract: Manumycin A: Synthesis of the (+)-Enantiomer and Revision of Stereochemical Assignment.

L. ALCARAZ

L. ALCARAZ

Dep. Chem., Univ. York, Heslington, York YO10 5DD, UK

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G. MACDONALD

G. MACDONALD

Dep. Chem., Univ. York, Heslington, York YO10 5DD, UK

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J. P. RAGOT

J. P. RAGOT

Dep. Chem., Univ. York, Heslington, York YO10 5DD, UK

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N. LEWIS

N. LEWIS

Dep. Chem., Univ. York, Heslington, York YO10 5DD, UK

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R. J. K. TAYLOR

R. J. K. TAYLOR

Dep. Chem., Univ. York, Heslington, York YO10 5DD, UK

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First published: 19 June 2010

Abstract

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ChemInform Abstract

The first total synthesis of the unnatural enantiomer (+)-manumycin A (IX) leads to a revision of the published structure (X) of the natural product, isolated from Streptomyces parvulus, to the C-4 epimer.

chemical structure image

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