Heterocyclic Compounds
Full Access
ChemInform Abstract: Lewis Acid Catalyzed Reaction of 2-Isopropenylaniline with Ketones: Improved Synthesis of 2,2,4-Trisubstituted 1,2-Dihydroquinolines.
First published: 19 June 2010
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
BF3×OEt2-Mediated condensation of 2-isopropenylaniline (I) with ketones affords title compounds (III). Sterically hindered ketones such as (Ic) and (Id) give low or no yields. The reaction proceeds via initial formation of an imine which can be isolated in the case of benzophenone.
