Heterocyclic Compounds
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ChemInform Abstract: Anti-Helicobacter pylori Agents. Part 2. Structure Activity Relationships in a New Series of 2-Alkylguanidino-4-furylthiazoles.
First published: 19 June 2010
Abstract
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ChemInform Abstract
Structure—activity relationships are investigated for a series of title compounds (VI). Among them derivatives (VIa) and (VId) are found to be potent and selective inhibitors of Helicobacter pylori. This activity depends on the length, unpolarity of substituents and also on the number of substituents at the guanidino moiety.
