Volume 29, Issue 31
Natural Products
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ChemInform Abstract: Stereoselective Synthesis of (2S,3R)-N-Boc-3-hydroxyglutamic Acid.

G. VEERESA

G. VEERESA

Org. Chem. Div., Indian Inst. Chem. Technol., Hyderabad 500 007, India

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A. DATTA

A. DATTA

Org. Chem. Div., Indian Inst. Chem. Technol., Hyderabad 500 007, India

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First published: 20 June 2010

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract

An efficient route to the non-proteinogenic title amino acid (X) is developed. The route is based on a chelation-controlled diastereoselective addition of benzylmagnesium chloride (II) to the aldehyde derived from (I) providing the syn amino alcohol (III).

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