Volume 29, Issue 31
Heterocyclic Compounds
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ChemInform Abstract: Synthesis of 4-Alkyl- or 4-Phenyl-7-methyl-1,2-dihydro-7H-imidazo[1,2,3-cd]purine-6,8-diones.

O. SIMO

O. SIMO

Inst. Chem., Slovak Acad. Sci., SK-842 38 Bratislava, Slovakia

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A. RYBAR

A. RYBAR

Inst. Chem., Slovak Acad. Sci., SK-842 38 Bratislava, Slovakia

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J. ALFOELDI

J. ALFOELDI

Inst. Chem., Slovak Acad. Sci., SK-842 38 Bratislava, Slovakia

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First published: 20 June 2010

Abstract

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ChemInform Abstract

The title tricycles (V) are prepared by intramolecular alkylation of mesylated hydroxyethyl purinediones (IV), which are obtained from the corresponding N-hydroxyethyl nitrosopyrimidines (I) by reduction and cyclization with orthocarboxylate (III).

chemical structure image

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