ChemInform Abstract: Synthesis of 4-Alkyl- or 4-Phenyl-7-methyl-1,2-dihydro-7H-imidazo[1,2,3-cd]purine-6,8-diones.
Abstract
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ChemInform Abstract
The title tricycles (V) are prepared by intramolecular alkylation of mesylated hydroxyethyl purinediones (IV), which are obtained from the corresponding N-hydroxyethyl nitrosopyrimidines (I) by reduction and cyclization with orthocarboxylate (III).