Volume 29, Issue 1
Heterocyclic Compounds
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ChemInform Abstract: Synthesis and NMR-Spectroscopic Investigation of Pyrazolo[1,5-a]pyrimidine Derivatives.

V. A. MAKAROV

V. A. MAKAROV

Tsentr khim. lek. sredstv-Vseross. nauchno-issled. khim.-farm. inst., Moskva 119815, Russia

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N. P. SOLOV'EVA

N. P. SOLOV'EVA

Tsentr khim. lek. sredstv-Vseross. nauchno-issled. khim.-farm. inst., Moskva 119815, Russia

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V. G. GRANIK

V. G. GRANIK

Tsentr khim. lek. sredstv-Vseross. nauchno-issled. khim.-farm. inst., Moskva 119815, Russia

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First published: 24 June 2010

Abstract

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ChemInform Abstract

The reaction of diaminonitropyrazole (I) with unsymmetrical β-dicarbonyls (II) prooceds regioselectively to give the 7-oxo-pyrazolopyrimidines (III). A similar reaction proceeds with the enaminoketones (VI) and (IX). The pyrazolopyrimidines (III), (VIIa), and (X) are used for further reaction with dimethylformamide diethylacetal to produce Schiff bases, which are characterized by NMR.

chemical structure image

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