Volume 29, Issue 1
Heterocyclic Compounds
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ChemInform Abstract: Serotonin 5-HT4 Agonist Activity of a Series of meso-Azanoradamantane Benzamides.

D. P. BECKER

D. P. BECKER

Dep. Med. Chem., G. D. Searle Co., Skokie, IL 60077, USA

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R. NOSAL

R. NOSAL

Dep. Med. Chem., G. D. Searle Co., Skokie, IL 60077, USA

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C. I. VILLAMIL

C. I. VILLAMIL

Dep. Med. Chem., G. D. Searle Co., Skokie, IL 60077, USA

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G. GULLIKSON

G. GULLIKSON

Dep. Med. Chem., G. D. Searle Co., Skokie, IL 60077, USA

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C. MOUMMI

C. MOUMMI

Dep. Med. Chem., G. D. Searle Co., Skokie, IL 60077, USA

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D.-C. YANG

D.-C. YANG

Dep. Med. Chem., G. D. Searle Co., Skokie, IL 60077, USA

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D. L. FLYNN

D. L. FLYNN

Dep. Med. Chem., G. D. Searle Co., Skokie, IL 60077, USA

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First published: 24 June 2010

Abstract

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ChemInform Abstract

With a view to the interesting biological properties of the corresponding chiral azaadamantane and azanoradamantane benzamides the non-chiral title compounds, e.g. (VII) and (XIII) are prepared. (VII) is the most potent azanoradamantane examined.

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