Heterocyclic Compounds
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ChemInform Abstract: Simple and Condensed β-Lactams. Part 29. Synthesis and Base-Catalyzed Ring Transformation of 4-[(2RS,3SR)-3-Hydroxy-1-(4-methoxyphenyl)-4-oxoazetidin-2-yl] thiazol-2(3H)-one.
First published: 24 June 2010
Abstract
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ChemInform Abstract
The azetidinylthiazolone (XII) is rearranged into the thiazolopyrazine derivative (XIII) on treatment with Na2CO3 under mild conditions. In contrast, the chlorophenoxy derivative (XIV) is stable under the same conditions.
