Volume 29, Issue 1
Heterocyclic Compounds
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ChemInform Abstract: Suzuki-Type Cross-Coupling Reaction of 1-Benzyl-2-iodo-1H-benzimidazoles with Aryl Boronic Acids: A Regioselective Route to N-Alkylated 6-Alkoxy-2-aryl-1H-benzimidazoles.

J. EZQUERRA

J. EZQUERRA

Cent. Invest. Lilly S. A., E-28130 Valdeolmos, Madrid, Spain

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C. LAMAS

C. LAMAS

Cent. Invest. Lilly S. A., E-28130 Valdeolmos, Madrid, Spain

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A. PASTOR

A. PASTOR

Cent. Invest. Lilly S. A., E-28130 Valdeolmos, Madrid, Spain

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J. L. GARCIA-NAVIO

J. L. GARCIA-NAVIO

Cent. Invest. Lilly S. A., E-28130 Valdeolmos, Madrid, Spain

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J. J. VAQUERO

J. J. VAQUERO

Cent. Invest. Lilly S. A., E-28130 Valdeolmos, Madrid, Spain

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First published: 24 June 2010

Abstract

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ChemInform Abstract

The Suzuki-type cross-coupling represents a new regioselective and convergent approach to 6-substituted 2-aryl-1H-benzimidazoles (XIII) (8 examples), which are required as synthons for new drugs.

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