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ChemInform Abstract: Mild and Regiospecific Phosphorylation of Nucleosides.
First published: 02 August 2010
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
Titration of a dry polystyrene diphenylphosphine with an iodine solution provides a polymeric phosphine-iodine complex which is an effective condensing agent for the phosphorylation of nucleosides. The reaction is regiospecific towards the primary hydroxyl group (cf. (IIb) ), and the inversion of the configuration at C-3′, unlike Mitsunobu reaction, is avoided.
