ChemInform Abstract: Synthesis and Evaluation of Benzophenone-Based Photoaffinity Labeling Analogues of Prenyl Pyrophosphates Containing Stable Amide Linkages.
Abstract
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ChemInform Abstract
The synthesis of two photoreactive prenyl pyrophosphate analogues (VII) and (VIII), which prove to be competitive inhibitors of yeast farnesyl protein transferase with respect to farnesyl pyrophosphate is described.