Volume 28, Issue 50
Preparative Organic Chemistry
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ChemInform Abstract: Oxygenation Reaction of Methyl Valproate with a Mono-oxygenase Model Reagent: Implication for Stereochemical Identification of the Mammalian Metabolites of Valproic Acid.

E. KOTANI

E. KOTANI

Showa Coll. Pharm. Sci., Machida, Tokyo 194, Japan

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T. TAKEYA

T. TAKEYA

Showa Coll. Pharm. Sci., Machida, Tokyo 194, Japan

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M. YOSHIIKE

M. YOSHIIKE

Showa Coll. Pharm. Sci., Machida, Tokyo 194, Japan

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A. WATANABE

A. WATANABE

Showa Coll. Pharm. Sci., Machida, Tokyo 194, Japan

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S. TOBINAGA

S. TOBINAGA

Showa Coll. Pharm. Sci., Machida, Tokyo 194, Japan

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First published: 02 August 2010

Abstract

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ChemInform Abstract

With a view to getting interesting informations which may be useful in identifying the stereochemical features of the mammalian metabolites of valproic acid the title model reaction is performed. Additionally, the chiral form of the racemic lactone (VII) is synthesized.

chemical structure image

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