ChemInform Abstract: Phosphono Analogues of Glutathione as New Inhibitors of Glutathione S- Transferases.
Abstract
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ChemInform Abstract
Title analogues such as (I) are obtained by solution phase peptide synthesis. The most active one of this new class of inhibitors is compound (Id) with an IC50 of 21 μM against the human placental glutathione S-transferases.