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ChemInform Abstract: 3-Alkylpyridines. Part 3. Total Synthesis of Both Enantiomers of the Antineoplastic Marine Alkaloid Niphatesine D.
First published: April 30, 1996
Abstract
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ChemInform Abstract
A facile five-step synthesis of the naturally occurring marine alkaloid niphatesine D (S)-(VII), starting from the readily available enantiomerically pure acetoxyalkylthiophene (I), is described. In an analogous manner the unnatural R-enantiomer of (VII) is prepared starting from (R)-(I).
