Heterocyclic Compounds
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ChemInform Abstract: New 2,3-Substituted 4,7-Dihydro-6-(1′H-pyrazol-3′-yl)pyrazolo(1,5-a) pyrimidin-7-ones and Related Compounds: Synthesis and Benzodiazepine Receptor Binding Study.
First published: April 30, 1996
Abstract
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ChemInform Abstract
Two new series of 6-(pyrazolyl)pyrazolopyrimidinones (cf. (IV); 18 examples) and -pyrimidines (cf. (VI); 6 examples) are synthesized and their in vitro benzodiazepine receptor affinity is determined. A plausible mechanistic pathway to the target compounds and several structure-affinity relationships are given.
