ChemInform Abstract: Fluoro-Decarboxylation of Pyrrolecarboxylic Acids by F-TEDA-BF4 - A Convenient General Synthesis of Fluoropyrroles.
Abstract
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ChemInform Abstract
A convenient general method for the synthesis of the title fluoro compounds such as (II) and (IV) is presented. Compound (IV) is an intermediate which on saponification leads to 2-fluoroporphobilinogen which may be useful as an inhibitor of the enzyme porphobilinogen deaminase.