ChemInform Abstract: Stereocontrolled Functionalization at the C-9 of Retinal. Stereoselective Synthesis of 9-trans-9-Fluororetinal.
Abstract
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ChemInform Abstract
A new synthetic strategy for the synthesis of C-9 functionalized retinal with 9-trans-selectivity is reported. Products (VII)/(VIII) are converted to 9-trans-9-fluororetinal via stereo- and regioselective isomerization.