ChemInform Abstract: Novel 5α-Reductase Inhibitors. Synthesis and Structure-Activity Studies of 5-Substituted 1-Methyl-2-pyridones and 1-Methyl-2- piperidones.
Abstract
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ChemInform Abstract
Among several tested title compounds, the shown examples (III)-(VI) exhibit the best results in in vitro tests for the biological activity mentioned in the title. (III) are stronger inhibitors than (IV).