Volume 26, Issue 19
Heterocyclic Compounds
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ChemInform Abstract: Synthesis of Activated Disulfide Adducts (VI) and (VII) Containing a 4- Diazocyclohexa-2,5-dienone Precursor for Photoaffinity Labelling.

C. DUGAVE

C. DUGAVE

Dep. Ing. Etude Proteines, F-91191 Gif-sur-Yvette, Fr.

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P. KESSLER

P. KESSLER

Dep. Ing. Etude Proteines, F-91191 Gif-sur-Yvette, Fr.

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First published: May 9, 1995

Abstract

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ChemInform Abstract

The pyridylsulfide-activated compound (VI) reacts with cysteine- containing peptides to generate photoactivatable and cleavable peptides. Attempts to introduce the title compounds after diazotation directly into the peptide, lead to decomposition.

chemical structure image

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