ChemInform Abstract: Synthesis of Activated Disulfide Adducts (VI) and (VII) Containing a 4- Diazocyclohexa-2,5-dienone Precursor for Photoaffinity Labelling.
Abstract
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ChemInform Abstract
The pyridylsulfide-activated compound (VI) reacts with cysteine- containing peptides to generate photoactivatable and cleavable peptides. Attempts to introduce the title compounds after diazotation directly into the peptide, lead to decomposition.