Volume 26, Issue 9
Organoelement Compounds
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ChemInform Abstract: Synthesis and Glutamate Antagonist Activity of 4- Phosphonoalkylquinoline Derivatives: A Novel Class of Non-NMDA Antagonists.

G. S. HAMILTON

G. S. HAMILTON

Scios Nova Inc., Baltimore, MD 21224, USA

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D. BEDNAR

D. BEDNAR

Scios Nova Inc., Baltimore, MD 21224, USA

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S. A. BOROSKY

S. A. BOROSKY

Scios Nova Inc., Baltimore, MD 21224, USA

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Z. HUANG

Z. HUANG

Scios Nova Inc., Baltimore, MD 21224, USA

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R. ZUBROWSKI

R. ZUBROWSKI

Scios Nova Inc., Baltimore, MD 21224, USA

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J. W. FERKANY

J. W. FERKANY

Scios Nova Inc., Baltimore, MD 21224, USA

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E. W. KARBON

E. W. KARBON

Scios Nova Inc., Baltimore, MD 21224, USA

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First published: February 28, 1995

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract

Several title compounds, e.g. (IV), (V) and (X), demonstrate significant antagonism at 6-cyano-7-nitroquinoxalin-2,3-dione (CNQX) binding sites and the glycine regulatory site of the NMDA receptor.

chemical structure image

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