Isocyclic Compounds
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ChemInform Abstract: An Efficient Method for the Synthesis of Guanidino Prodrugs.
First published: February 28, 1995
Abstract
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ChemInform Abstract
The esterase-activatable quanidino prodrugs (V) significantly improve the permeability coefficients in Caco-2 cell monolayers. These results would predict increased oral absorption in vivo.
