ChemInform Abstract: Chemoselective Nucleophilic Attack of α,α-Dicyano Epoxides: A Simple Synthesis of α-Amino Amides, Epoxy Amidines and Their Cyclic Analogues.
Abstract
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ChemInform Abstract
The course of the title reaction depends on the substitution pattern of the epoxides. The reaction of (I) with different amines is found to be quite general and opens a new route to the classes of title compounds.