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ChemInform Abstract: Synthesis of an Oxyamide Linked Nucleotide Dimer and Incorporation into Antisense Oligonucleotide Sequences.
First published: August 30, 1994
Abstract
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ChemInform Abstract
The oxyamide linked nucleotide dimer (VIII) is synthesized by using the thymidine derivative (I) as starting material. The dimer is shown to anneal to complementary DNA with nearly the same affinity as the natural sequence.
