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ChemInform Abstract: Synthesis of Philanthotoxin Analogues with a Branched Polyamine Moiety.
First published: March 29, 1994
Abstract
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ChemInform Abstract
General methods are developed for the synthesis of philanthotoxin analogues such as (VIII) with branched polyamine side chains. The procedure is based on the reductive amination of an appropriately substituted, protected amino aldehyde (V) with a primary amine (VI).
