Volume 25, Issue 13
Heterocyclic Compounds
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ChemInform Abstract: A New Method for the Preparation of Tetrazoles from Nitriles Using Trimethylsilylazide/Trimethylaluminum.

B. E. HUFF

B. E. HUFF

Lilly Res. Lab., Lilly Corp. Cent., Eli Lilly Co., Indianapolis, IN 46285, USA

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M. A. STASZAK

M. A. STASZAK

Lilly Res. Lab., Lilly Corp. Cent., Eli Lilly Co., Indianapolis, IN 46285, USA

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First published: March 29, 1994

Abstract

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ChemInform Abstract

A series of ten tetrazoles such as (III) are prepared in a convenient manner by trimethylaluminum-mediated reaction of the corresponding nitriles (I) with trimethylsilyl azide in hot toluene.

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