Volume 24, Issue 14
Heterocyclic Compounds
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ChemInform Abstract: A Novel Synthesis of 2-Aminochromones via Phosgeniminium Salts.

J. MORRIS

J. MORRIS

Med. Chem. Res., Upjohn Co., Kalamazoo, MI 49001, USA

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D. G. WISHKA

D. G. WISHKA

Med. Chem. Res., Upjohn Co., Kalamazoo, MI 49001, USA

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Y. FANG

Y. FANG

Med. Chem. Res., Upjohn Co., Kalamazoo, MI 49001, USA

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First published: April 6, 1993

Abstract

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ChemInform Abstract

The conversion of the 2-hydroxyacetophenones (I) to their BF2-- complexes, followed by treatment with the phosgeniminium chlorides (II) and hydrolysis of the intermediate β-chloro vinylogous amide - BF2--complex produces the 2-aminochromones (III).

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