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ChemInform Abstract: Development of New Protecting Groups for Guanine Residue in Oligodeoxyribonucleotide Synthesis.
First published: October 1, 1991
Abstract
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ChemInform Abstract
The dimethylcarbamoyl group is the most promising group in combination with the phenylacetyl group for the protection of the deoxyguanosine ( I). This most stable of several protecting groups is successfully applied in the synthesis of d(AAGCTT) hexanucleotide, which is Hind III recognition sequence.
