Heterocyclic Compounds
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ChemInform Abstract: Research on Psychotropic Agents. Part 3. Antidepressant Activity and Neuropsychobehavioural Effects of New 5H-Pyrrolo(1,2-b)(1,2,5)benzotriazepine Derivatives.
First published: September 11, 1990
Abstract
The benzotriazepines (III) and (VIII) are prepared from the anilines (II) and (VII) by reaction with the aldehydes (I).
ChemInform Abstract
The benzotriazepines (III) and (VIII) are prepared from the anilines (II) and (VII) by reaction with the aldehydes (I). The derivatives (XI) are synthesized via acylation of (VII) and subsequent cyclocondensation. The compounds (III) have antidepressant activity and sedative effects. The derivatives (VIII) and (XI) show lower antidepressant activity, but give remarkable sedative effects.
