Volume 21, Issue 37
Heterocyclic Compounds
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ChemInform Abstract: Synthesis of 2-(1,2-Dihydropyrazol-4-yl)-1,3,4-thiadiazole Derivatives as Potential Antimicrobial Agents.

G. AUZZI

G. AUZZI

Dip. Sci. Farm., Univ., 50121 Firenze, Italy

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F. BRUNI

F. BRUNI

Dip. Sci. Farm., Univ., 50121 Firenze, Italy

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M. CLAUSER

M. CLAUSER

Dip. Sci. Farm., Univ., 50121 Firenze, Italy

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G. CICIANI

G. CICIANI

Dip. Sci. Farm., Univ., 50121 Firenze, Italy

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A. COSTANZO

A. COSTANZO

Dip. Sci. Farm., Univ., 50121 Firenze, Italy

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L. PECORI VETTORI

L. PECORI VETTORI

Dip. Sci. Farm., Univ., 50121 Firenze, Italy

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R. DONATO

R. DONATO

Dip. Sci. Farm., Univ., 50121 Firenze, Italy

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First published: September 11, 1990

Abstract

The pyrazoledithiocarboxylic acids (I) are converted to the thiohydrazides (III).

ChemInform Abstract

The pyrazoledithiocarboxylic acids (I) are converted to the thiohydrazides (III). These undergo cyclocondensation with the ortho esters (IV), forming the title compounds (V). The derivatives (VI) are prepared from (V) by deacylation. The title compounds (V) and (VI) do not have antimicrobial activity. (No yields given).

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