Volume 21, Issue 37
Isocyclic Compounds
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ChemInform Abstract: Crossed Aldol-Type Condensation Reactions in Aqueous Media.

T. H. CHAN

T. H. CHAN

Dep. Chem., McGill Univ., Montreal, Que. H3A 2K6, Can.

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C. J. LI

C. J. LI

Dep. Chem., McGill Univ., Montreal, Que. H3A 2K6, Can.

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Z. Y. WEI

Z. Y. WEI

Dep. Chem., McGill Univ., Montreal, Que. H3A 2K6, Can.

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First published: September 11, 1990

Abstract

The aldehydes (I) are coupled with the α-bromo ketones (II) in the presence of metallic zinc to produce the β-hydroxy ketones (III).

ChemInform Abstract

The aldehydes (I) are coupled with the α-bromo ketones (II) in the presence of metallic zinc to produce the β-hydroxy ketones (III). This reaction also succeeds, when metallic tin or chloro ketones are employed. Further examples are given in the original paper. (Intermediates).

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