ChemInform Abstract: The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). Part 21. A Mild Process for the Application of 10-Alkyl-9-acridanones and Its Application to the Synthesis of Acridone Alkaloids.
Abstract
10-Substituted-9-acridanones such as (IV) are readily prepared by the reaction of the isatoic anhydride (I) with 2-cyclohexenone (II) and subsequent aromatization.
ChemInform Abstract
10-Substituted-9-acridanones such as (IV) are readily prepared by the reaction of the isatoic anhydride (I) with 2-cyclohexenone (II) and subsequent aromatization. Two alkaloids, i.e. 1,2,3-trimethoxy-10-methylacridone (VIIIa) and evoxanthine (VIIIb), are prepared by this method.