Volume 21, Issue 1
Isocyclic Compounds
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ChemInform Abstract: An Electrophile-Assisted Nonsolvent Synthesis of Alkyl Macroisocyclic Ethers: An Improved Nonsolvent Williamson Synthesis of Medium-Sized Alkyl Carbocyclic Ethers.

J. J. CHAPMAN

J. J. CHAPMAN

Lorillard, Inc., Lorillard Res. Center, Greensboro, NC 27420-1688, USA

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J. R. REID

J. R. REID

Lorillard, Inc., Lorillard Res. Center, Greensboro, NC 27420-1688, USA

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First published: January 2, 1990

ChemInform Abstract

The macrocyclic alcohols (I) react with the alkyl halides (II) and sodium hydride in the absence of solvents to give the ethers (III).

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