Organoelement Compounds
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ChemInform Abstract: Chirality Transfer from Silicon to Carbon: Use of Optically Pure Cyclic Silanes with a Binaphthalene Chiral Unit.
First published: May 30, 1989
Abstract
1-Bromo-2-methylnaphthalene (I) is dimerized to yield the racemic binaphthalene (II) which is optically resolved via bromination and separation of the diastereomeric ephedrine salts.
ChemInform Abstract
1-Bromo-2-methylnaphthalene (I) is dimerized to yield the racemic binaphthalene (II) which is optically resolved via bromination and separation of the diastereomeric ephedrine salts. (S)-(II) is converted to the chiral hydrosilane (S)-(V) which is employed in various reactions, e.g. in the reduction of the ketones (VI), yielding the alcohols (VII) with moderate optical purity.
