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ChemInform Abstract: Steroids. Part 40. 15-(Hydroxymethyl)androstene and -estratriene Derivatives.
First published: January 10, 1989
Abstract
The reduction of the steroid (Ib) gives two isomers (III) and the seco derivative (IV).
ChemInform Abstract
The reduction of the steroid (Ib) gives two isomers (III) and the seco derivative (IV). After hydrolysis of the tetrahydropyranyl groups, the same compound (V) is obtained either from (IIIa) or (IIIb). Similarly, the other title compound (VII) is prepared by reduction of the estratriene derivative (VI). - The configurations of the chiral centers are determined, inter alia, by chemical reactions. In this context, a transformation of the derivative (VIII) to the compounds (X) and (XI) is described.
