ChemInform Abstract: One-Step Synthesis of 2-Aminothieno(2,3-e)(1,3)thiazin-4-ones in Some Cases 5,6-Anellated from Ethyl 2-Benzoylthioureidothiophene-3-carboxylates and Evaluation of Their Antiallergic Activity.
Abstract
Reaction of the aminothiophenecarboxylates (I) with the isothiocyanate (II) yields the thioureas (III) which are cyclized under acidic conditions, forming the thienothiazines (IV).
ChemInform Abstract
Reaction of the aminothiophenecarboxylates (I) with the isothiocyanate (II) yields the thioureas (III) which are cyclized under acidic conditions, forming the thienothiazines (IV). Their antiallergic activity is determined.