Heterocyclic Compounds
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ChemInform Abstract: Intramolecular Alkylations of Aromatic Compounds. Part 21. Synthesis of cis-4,10b-Dimethyl-1,2,3,4,4a,5,5a,10b-octahydroindano(1,7-f,g)quinoline.
First published: January 10, 1989
Abstract
Indanone (I) is coupled with the lutidine (II) to yield the pyridinylmethylindanol (III) which is dehydrated and then hydrogenated, forming the pyridinylmethylindan (IV).
ChemInform Abstract
Indanone (I) is coupled with the lutidine (II) to yield the pyridinylmethylindanol (III) which is dehydrated and then hydrogenated, forming the pyridinylmethylindan (IV). Methylation gives the pyridinium salt (VI). This is reduced and subsequently cyclized, forming the indanoquinoline (VIII).
