Heterocyclic Compounds
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ChemInform Abstract: 1,4-Dihydro- and 2,4-Dihydropyrrolo(3,4-b)indoles with Donor Groups in the 3-Position.
First published: January 10, 1989
Abstract
Acid-promoted dealkylation of the N-tert-butyl lactam (I) yields the lactam (II) which is converted into the methoxy-1,4-dihydropyrroloindole (V) by methylation with the triflate (III) and subsequent deprotonation.
ChemInform Abstract
Acid-promoted dealkylation of the N-tert-butyl lactam (I) yields the lactam (II) which is converted into the methoxy-1,4-dihydropyrroloindole (V) by methylation with the triflate (III) and subsequent deprotonation. Sulfurization of the methoxypyrrolium salt (VI) gives the thiolactam (VII) which is methylated, producing the methylthio-2,4-dihydropyrroloindole (VIII). This is coupled with the maleimide (IX), forming the carbazole derivative (X).
