Preparative Organic Chemistry
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ChemInform Abstract: Reactions of Primary Amines and Hydrazines with Thiosuccinic and Thioglutaric Acid Esters.
First published: January 10, 1989
Abstract
Coupling of the dithiosuccinate (I) with the primary amines (II) or of the tetrathioglutarate (VIb) with (IIa) or benzylamine (IV) gives the amides (III) and (VII).
ChemInform Abstract
Coupling of the dithiosuccinate (I) with the primary amines (II) or of the tetrathioglutarate (VIb) with (IIa) or benzylamine (IV) gives the amides (III) and (VII). In contrast, treatment of (I) with (IV) leads to the formation of the pyrrolidine derivative (V). The pyridazine (IX) is obtained from (I) and the hydrazines (VIII), reaction of the esters (VIa) or (VIb) with (VIIIb) produces the dihydrazides (X).
