Volume 20, Issue 2
Preparative Organic Chemistry
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ChemInform Abstract: Reductive Cleavage of 4,5-Cycloalkanoisoxazolines.

F. A. LAKHVICH

F. A. LAKHVICH

Inst. bioorg. khim. AN Belorusskoi SSR, Minsk 220600

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V. A. KHRIPACH

V. A. KHRIPACH

Inst. bioorg. khim. AN Belorusskoi SSR, Minsk 220600

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A. N. PYRKO

A. N. PYRKO

Inst. bioorg. khim. AN Belorusskoi SSR, Minsk 220600

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I. P. ANTONEVICH

I. P. ANTONEVICH

Inst. bioorg. khim. AN Belorusskoi SSR, Minsk 220600

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T. V. YANKOVA

T. V. YANKOVA

Inst. bioorg. khim. AN Belorusskoi SSR, Minsk 220600

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E. V. KOROLEVA

E. V. KOROLEVA

Inst. bioorg. khim. AN Belorusskoi SSR, Minsk 220600

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A. A. AKHREM

A. A. AKHREM

Inst. bioorg. khim. AN Belorusskoi SSR, Minsk 220600

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First published: January 10, 1989

Abstract

Reductive cleavage of the anellated isoxazolines (I) with Raney-nickel in the presence of acids gives the dihydroxy ketones (II) and/or its dehydration products (III).

ChemInform Abstract

Reductive cleavage of the anellated isoxazolines (I) with Raney-nickel in the presence of acids gives the dihydroxy ketones (II) and/or its dehydration products (III). Yields and product ratios widely depend on the reaction conditions.

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