Heterocyclic Compounds
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ChemInform Abstract: Nucleophilic Substitution at C-4 in 4-Functionalized Hexahydropyrimidine-2-thiones. Synthesis of 4-Alkylthiohexahydropyrimidine-2-thiones.
First published: August 16, 1988
Abstract
Reaction of the hydroxyhexahydropyrimidinethiones (I) with the mercaptans (II) gives the alkylmercapto derivatives (III) with retention of the configuration.
ChemInform Abstract
Reaction of the hydroxyhexahydropyrimidinethiones (I) with the mercaptans (II) gives the alkylmercapto derivatives (III) with retention of the configuration. Methanolysis of (III) yields the methoxy compounds (V). (Mechanism).
