Heterocyclic Compounds
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ChemInform Abstract: Organic Azides in Heterocyclic Synthesis. Part 7. 4-Aminouracils and Pyrimido(4,5-b)indolediones from 4-Azidouracils.
First published: May 3, 1988
Abstract
Condensation of phenylmalonic acid (I) with the ureas (II) affords the barbituric acid derivatives (III), which are converted to the 4-azidouracils (V).
ChemInform Abstract
Condensation of phenylmalonic acid (I) with the ureas (II) affords the barbituric acid derivatives (III), which are converted to the 4-azidouracils (V). Starting from these the pyrimido(4,5-b)indolediones (VI) and the 4-aminouracil (VII) are prepared in high yields. Debenzylation of (VIb) affords the dione (VIII).
