Preparative Organic Chemistry
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ChemInform Abstract: The “ipso” Effect of Silicium in the Acylation of m-Trimethylsilylanisole.
First published: May 3, 1988
Abstract
Acylation of m-trimethylsilylanisole (I) using benzoyl chloride (II) or acetyl chloride (VII) gives the distribution of products as shown in the reaction scheme.
ChemInform Abstract
Acylation of m-trimethylsilylanisole (I) using benzoyl chloride (II) or acetyl chloride (VII) gives the distribution of products as shown in the reaction scheme. This result of the reaction demonstrates clearly that the ipso effect of the trimethylsilyl group is countered by the methoxy group.
