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ChemInform Abstract: Retinoids. Part 6. Preparation of Alkyl- and Trimethylsilyl-Substituted Retinoids via Conjugate Addition of Cuprates to Acetylenic Esters.
First published: September 1, 1987
Abstract
The acetylenic ester (Ib), prepared from β-ionone via (Ia), reacts selectively with the organocuprates (III) to form the adducts (IV), which are converted to the modified retinoids (VI).
ChemInform Abstract
The acetylenic ester (Ib), prepared from β-ionone via (Ia), reacts selectively with the organocuprates (III) to form the adducts (IV), which are converted to the modified retinoids (VI). The acetylenic ester (VIII), obtained from (VII), is transformed into the retinal derivatives (IX) in a similar manner.
